In the past hypothesis-driven research in the life sciences has been the domain of experimental biologists, with the role of biostatisticians and bioinformaticians being one of support. This is no longer the case. As the “data-deluge” continues my research interests are focused on how to use biological “big-data” in order to create and test hypotheses.
My primary research interest is in understanding how individual genes or sets of genes can coordinate changes in cellular phenotypes that can lead to disease or cellular trans-differentiation. I have approached this problem through the integration of varied data sources, the development of algorithms and close collaboration with experimental scientists in order to create testable predictions for the lab.
Centre for Computational Biology, 8 College Road, Singapore, 169857